Human Physiology

Paper Code: 
BPT 102
Credits: 
10
Max. Marks: 
100.00
Objective: 
  • Understand and demonstrate the interrelations of the organ systems to each other.
  • State the functions of each organ system of the body, explain the mechanisms by which each functions, and relate the functions and the anatomy and histology of each organ system.
  • Predict and explain the integrated responses of the organ systems of the body to physiological and pathological stresses.

 

Unit I: 
General Physiology
  1. Introduction and scope of Physiology. Cell and tissue – its structure, principal constituents, properties and function including cell division, Body fluids.
  2. Blood: Introduction-composition and general function of plasma. Blood cells – structure and function – Red blood cell, white blood cell – including number and approximate length of life – position structure and function of cell of reticulo-endothelial system.

Blood clotting including bleeding time and clotting time, factors accelerating or slowing the process. Blood groups and their significance, Rh- factor, haemostasis, Hemoglobin and E.S.R.

Formation of blood, tissue fluid and lymph-composition, formation ,circulation & functions.

 

Unit II: 
Cardiovascular System ( Detailed)

Cardiovascular System.

Structure and properties of Heart Muscles and nerve supply of Heat.

Structure and function of arteries, capillaries and veins.

Cardiac cycle and Heart sound.

Cardiac output measurements, factors affecting Heart Rate and its regulation,

Cardiac – vascular reflexes.

Bloods pressure, its regulation, physiological variation, peripheral resistance, Factors controlling blood pressure, Hemorrhage.

ECG study. Stress and stress test.

 

Unit III: 
Respiratory System (detailed):

Respiratory System.

Mechanism of Respiration, change in diameters of thorax – intra-pleural and intra-pulmonary pressure.

Quantities of lung volume, tidal and residual volume, vital capacity.

Gaseous inter-changes in lung and tissues.

Control of respiration – Nervous and chemical significance of change in rate and depth, transportation of oxygen and carbon-dioxide.

Respiratory states – anoxia, asphyxia, cyanosis, acclimatization.

 

Unit IV: 
Neuromuscular Physiology (Detailed)

      Cell membrane – ionic and potential gradient and transport. Muscle – Types of muscular tissue – Gross and microscopic structure – function, Basis of Muscle contraction – change in muscle contraction, Electrical – Biphasic and monophasic action potentials, chemical, Thermal and physical change, Isometric and Isotonic contraction.

Motor units and its properties – clonus, tetanus, all or none law, Fatigue.

Nerve – Gross and microscopic structure of nervous tissue, one neuron – Generation of action potential – Nerve impulse – condition.

Neuromuscular junction, Degeneration – Regeneration of peripheral nerves Wallerian degeneration, electro tonus and pfluger’s law.

Types and properties, of receptions, types of sensation, synapse, reflex, are its properties occlusion, summation, sub minimal fatigue ext.

Tracts – Ascending and descending and extra pyramidal tracts.

Function of E.E.G. ,Function of Cerebral cortex, cerebrum, cerebellum, Basal ganglia, Thalamus – connection and functions.Reticular formation – tone, posture & equilibrium, autonomic nervous system,

Special Senses Eye – Error of refraction, lesions of visual path ways, Speech and its disorder, Ear and vestibular apparatus, test, olfactory, somatic sensations.

 

Unit V: 
Digestive System (Details not required)

General arrangements of alimentary canal, stomach, gall bladder, spleen, liver pancreas small & large intestine and rectum  – position, structure and functions.

Nutrition and diet – carbohydrates, protein, fat, salt, water, vitamins and minerals digestion, Absorption and Metabolism.

 

Essential Readings: 

Gross and minute structure of kidney, renal circulation, Mechanism of formation of urine, Glomerular rate and tubular function, renal function and renal test. Physiology of micturition.

Endocrine System - Structure and function of pituitary (anterior & posterior). Thyroid, Parathyroid, adrenal cortex, adrenal medulla, Thymus and pancreas pineal, testical & ovarian hormones.

Blood sugar regulation.

Special senses and integumentary system

PRACTICAL :

  1. Hematology: - RBC counts, WBC count, different count ESR, Bleeding & Clotting time, Estimation of hemoglobin, Blood groups.
  2. Human physiology: - Examination of (a) Respiratory system (b) heart and arterial pulse (c) deep and superficial reflexes (d) cranial nerves (e) motor system. (f) Sensory system including higher function (g) measurement of blood pressure.
  3. Effect of exercises on body physiology.

 

 

References: 

Textbook of Medical Physiology – Arthur Guyton(Mosby.)

 2. K. Sembulingam – Essentials of Medical Physiology

 3. Human Physiology- Vol. 1&2 ,CC,Calcutta,Medical Allied

4. Textbook of Physiology :AK Jain.

5. Principals of Anatomy and Physiology – Tortora & Grabowski- Harper Collins

6. Textbook of Practical Physiology- Jaypee

 

Academic Year: 
Unit VI: 
Reproductive System
Unit VI Description: 
Sex determination and development of puberty, male sex hormones, spermatogenesis, female sex hormones, menstrual cycle. Ovulation, pregnancy, Function of placenta, location.
Unit VI Hours: 
Excretory System,Endocrine System,Special senses and integumentary system &PRACTICAL